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Year Number of Results
1979 1
1980 1
1981 1
1982 1
1983 2
1985 1
1986 1
1987 1
1988 1
1994 2
1995 1
1997 1
1999 1
2000 1
2002 2
2003 3
2004 2
2005 2
2006 2
2007 7
2008 4
2009 2
2010 6
2011 6
2012 10
2013 13
2014 20
2015 12
2016 10
2017 8
2018 16
2019 20
2020 24
2021 22
2022 28
2023 32
2024 16

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253 results

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Page 1
Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease.
Beck DB, Ferrada MA, Sikora KA, Ombrello AK, Collins JC, Pei W, Balanda N, Ross DL, Ospina Cardona D, Wu Z, Patel B, Manthiram K, Groarke EM, Gutierrez-Rodrigues F, Hoffmann P, Rosenzweig S, Nakabo S, Dillon LW, Hourigan CS, Tsai WL, Gupta S, Carmona-Rivera C, Asmar AJ, Xu L, Oda H, Goodspeed W, Barron KS, Nehrebecky M, Jones A, Laird RS, Deuitch N, Rowczenio D, Rominger E, Wells KV, Lee CR, Wang W, Trick M, Mullikin J, Wigerblad G, Brooks S, Dell'Orso S, Deng Z, Chae JJ, Dulau-Florea A, Malicdan MCV, Novacic D, Colbert RA, Kaplan MJ, Gadina M, Savic S, Lachmann HJ, Abu-Asab M, Solomon BD, Retterer K, Gahl WA, Burgess SM, Aksentijevich I, Young NS, Calvo KR, Werner A, Kastner DL, Grayson PC. Beck DB, et al. N Engl J Med. 2020 Dec 31;383(27):2628-2638. doi: 10.1056/NEJMoa2026834. Epub 2020 Oct 27. N Engl J Med. 2020. PMID: 33108101 Free PMC article.
In such patients, an often fatal, treatment-refractory inflammatory syndrome develops in late adulthood, with fevers, cytopenias, characteristic vacuoles in myeloid and erythroid precursor cells, dysplastic bone marrow, neutrophilic cutaneous and pulmonary inflammation, ch …
In such patients, an often fatal, treatment-refractory inflammatory syndrome develops in late adulthood, with fevers, cytopenias, characteri …
The role and regulation of Maf proteins in cancer.
Deng Y, Lu L, Zhang H, Fu Y, Liu T, Chen Y. Deng Y, et al. Biomark Res. 2023 Feb 7;11(1):17. doi: 10.1186/s40364-023-00457-w. Biomark Res. 2023. PMID: 36750911 Free PMC article. Review.
The Maf proteins (Mafs) belong to basic leucine zipper transcription factors and are members of the activator protein-1 (AP-1) superfamily. There are two subgroups of Mafs: large Mafs and small Mafs, which are involved in a wide range of biological processes, such as the c …
The Maf proteins (Mafs) belong to basic leucine zipper transcription factors and are members of the activator protein-1 (AP-1) superf …
Diet-induced gut dysbiosis and inflammation: Key drivers of obesity-driven NASH.
Kang GG, Trevaskis NL, Murphy AJ, Febbraio MA. Kang GG, et al. iScience. 2022 Dec 30;26(1):105905. doi: 10.1016/j.isci.2022.105905. eCollection 2023 Jan 20. iScience. 2022. PMID: 36691622 Free PMC article. Review.
Consumption of a high-caloric, western-style diet induces gut dysbiosis and inflammation resulting in leaky gut. Translocation of gut-derived bacterial content promotes hepatic inflammation and ER stress, and when either or both of these are combined with steatosis, …
Consumption of a high-caloric, western-style diet induces gut dysbiosis and inflammation resulting in leaky gut. Translocation of gut …
Integrated Bioinformatic Analysis of the Shared Molecular Mechanisms Between Osteoporosis and Atherosclerosis.
Mo L, Ma C, Wang Z, Li J, He W, Niu W, Chen Z, Zhou C, Liu Y. Mo L, et al. Front Endocrinol (Lausanne). 2022 Jul 22;13:950030. doi: 10.3389/fendo.2022.950030. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35937806 Free PMC article.
RESULTS: The results of common genes analysis showed that immune and inflammatory response may be a common feature in the pathophysiology of osteoporosis and atherosclerosis. Six hub genes (namely, COL1A1, IBSP, CTSD, RAC2, MAF, and THBS1) were obtained via taking interact …
RESULTS: The results of common genes analysis showed that immune and inflammatory response may be a common feature in the pathophysiology of …
Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes.
Fu Z, Gilbert ER, Liu D. Fu Z, et al. Curr Diabetes Rev. 2013 Jan 1;9(1):25-53. Curr Diabetes Rev. 2013. PMID: 22974359 Free PMC article. Review.
In addition, this review presents evidence that genetic and environmental factors can lead to hyperglycemia, dyslipidemia, inflammation, and autoimmunity, resulting in beta-cell dysfunction, thereby triggering the pathogenesis of diabetes....
In addition, this review presents evidence that genetic and environmental factors can lead to hyperglycemia, dyslipidemia, inflammation
Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism.
von Scheidt M, Zhao Y, de Aguiar Vallim TQ, Che N, Wierer M, Seldin MM, Franzén O, Kurt Z, Pang S, Bongiovanni D, Yamamoto M, Edwards PA, Ruusalepp A, Kovacic JC, Mann M, Björkegren JLM, Lusis AJ, Yang X, Schunkert H. von Scheidt M, et al. Circulation. 2021 May 4;143(18):1809-1823. doi: 10.1161/CIRCULATIONAHA.120.050186. Epub 2021 Feb 25. Circulation. 2021. PMID: 33626882 Free PMC article.
Chromatin immunoprecipitation mass spectrometry revealed that the human CAD genome-wide association studies candidate BACH1 (BTB domain and CNC homolog 1) assists MAFF in the presence of lipopolysaccharide stimulation with respective heterodimers binding at the MAF recogni …
Chromatin immunoprecipitation mass spectrometry revealed that the human CAD genome-wide association studies candidate BACH1 (BTB domain and …
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis.
Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Lee YC, Todd DJ, Bykerk VP, Goodman SM, Pernis AB, Ivashkiv LB, Karlson EW, Nigrovic PA, Filer A, Buckley CD, Lederer JA, Raychaudhuri S, Brenner MB. Rao DA, et al. Nature. 2017 Feb 1;542(7639):110-114. doi: 10.1038/nature20810. Nature. 2017. PMID: 28150777 Free PMC article.
Rather, using multidimensional cytometry, transcriptomics, and functional assays, we define a population of PD-1(hi)CXCR5(-) 'peripheral helper' T (T(PH)) cells that express factors enabling B-cell help, including IL-21, CXCL13, ICOS, and MAF. Like PD-1(hi)CXCR5(+) T folli …
Rather, using multidimensional cytometry, transcriptomics, and functional assays, we define a population of PD-1(hi)CXCR5(-) 'peripheral hel …
c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont.
Xu M, Pokrovskii M, Ding Y, Yi R, Au C, Harrison OJ, Galan C, Belkaid Y, Bonneau R, Littman DR. Xu M, et al. Nature. 2018 Feb 15;554(7692):373-377. doi: 10.1038/nature25500. Epub 2018 Feb 7. Nature. 2018. PMID: 29414937 Free PMC article.
There is accumulating evidence that microbial species that potentiate chronic inflammation, as in inflammatory bowel disease, often also colonize healthy individuals. ...By contrast, RORgammat inactivation in T(reg) cells had only a minor effect on the bacteria-specific T( …
There is accumulating evidence that microbial species that potentiate chronic inflammation, as in inflammatory bowel disease, often a …
253 results